Primary pure intratesticular fibrosarcoma

Pathol Int. 1999 Feb;49(2):185-9. doi: 10.1046/j.1440-1827.1999.00844.x.

Abstract

Testicular sarcoma appears to be a rare stromal tumor usually of indolent course with potential for distant metastases. A pure primary intratesticular fibrosarcoma in a 71-year-old male is presented. By the time the tumor became evident metastases had already occurred widely. The course was rapidly fatal. A review of the literature yielded only one case reported previously. The present case illustrates that pure fibrosarcoma occurs occasionally as a stromal tumor and may be associated with a dismal prognosis. The diagnosis of pure fibrosarcoma should be made only after extensive sampling of the testicular tumor to rule out an associated germ cell component. The differential diagnosis also includes the fibroma of gonadal stroma origin and the unclassified sex cord-stromal tumor with a predominance of spindle cells.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biomarkers, Tumor / analysis
  • Bone Neoplasms / chemistry
  • Bone Neoplasms / secondary*
  • Bone Neoplasms / surgery
  • Diagnosis, Differential
  • Fatal Outcome
  • Fibrosarcoma / chemistry
  • Fibrosarcoma / secondary*
  • Fibrosarcoma / surgery
  • Humans
  • Immunoenzyme Techniques
  • Liver Neoplasms / chemistry
  • Liver Neoplasms / secondary*
  • Liver Neoplasms / surgery
  • Lung Neoplasms / chemistry
  • Lung Neoplasms / secondary*
  • Lung Neoplasms / surgery
  • Male
  • Retroperitoneal Neoplasms / chemistry
  • Retroperitoneal Neoplasms / secondary*
  • Retroperitoneal Neoplasms / surgery
  • Sex Cord-Gonadal Stromal Tumors / pathology
  • Stromal Cells / pathology
  • Testicular Neoplasms / chemistry
  • Testicular Neoplasms / pathology*
  • Testicular Neoplasms / surgery

Substances

  • Biomarkers, Tumor