Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1999 Jun;9(3):408-15.
doi: 10.1016/S0959-440X(99)80055-4.

Protein Families in Multicellular Organisms

Affiliations
Review

Protein Families in Multicellular Organisms

R R Copley et al. Curr Opin Struct Biol. .

Abstract

The complete sequence of the nematode worm Caenorhabditis elegans contains the genetic machinery that is required to undertake the core biological processes of single cells. However, the genome also encodes proteins that are associated with multicellularity, as well as others that are lineage-specific expansions of phylogenetically widespread families and yet more that are absent in non-nematodes. Ongoing analysis is beginning to illuminate the similarities and differences among human proteins and proteins that are encoded by the genomes of the multicellular worm and the unicellular yeast, and will be essential in determining the reliability of transferring experimental data among phylogenetically distant species.

Similar articles

See all similar articles

Cited by 16 articles

See all "Cited by" articles

LinkOut - more resources

Feedback