Muscle substrate utilization and lactate production

Can J Appl Physiol. 1999 Jun;24(3):209-15. doi: 10.1139/h99-017.

Abstract

Biopsies (biceps) were examined in 8 bodybuilders across a typical arm-curl training session (80% 1-RM). [PCr] and [glycogen] decreased 62 and 12% after 1 set (n = 4), and 50 and 24% after 3 sets (n = 4). [Lactate] was 91 and 118 mmol &times kg-1, respectively, after 1 and 3 sets. Fatigue was probably partially caused by decreased [PCr] and increased [H+] (first set) and by decreased [H+] in subsequent sets.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Triphosphate / analysis
  • Adenosine Triphosphate / metabolism
  • Adult
  • Analysis of Variance
  • Arm / physiology
  • Biopsy, Needle
  • Glycogen / analysis
  • Glycogen / metabolism*
  • Humans
  • Hydrogen / metabolism
  • Lactic Acid / biosynthesis*
  • Lactic Acid / blood
  • Male
  • Muscle Contraction / physiology
  • Muscle Fatigue / physiology
  • Muscle, Skeletal / chemistry
  • Muscle, Skeletal / metabolism*
  • Phosphocreatine / analysis
  • Phosphocreatine / metabolism*
  • Weight Lifting / physiology*

Substances

  • Phosphocreatine
  • Lactic Acid
  • Hydrogen
  • Adenosine Triphosphate
  • Glycogen