Anticatabolic action of formebolone in the castrated rat treated with dexamethasone

Arzneimittelforschung. 1976;26(9):1673-7.

Abstract

The anticatabolic action of 2-formyl-17a-methylandrosta-1,4-diene-11a,17beta-diol-3-one (formebolone) was demonstrated by assessing the nitrogen elimination in the urine of castrated rats treated with dexamethasone-21-phosphate. The absence of a virilizing action is duly pointed out.

MeSH terms

  • Anabolic Agents / pharmacology*
  • Androstenediols / pharmacology*
  • Animals
  • Body Weight / drug effects
  • Castration
  • Dexamethasone / antagonists & inhibitors*
  • Ketosteroids / pharmacology
  • Male
  • Metabolism / drug effects*
  • Muscles / drug effects
  • Nitrogen / metabolism
  • Organ Size
  • Rats
  • Seminal Vesicles / drug effects

Substances

  • Anabolic Agents
  • Androstenediols
  • Ketosteroids
  • Dexamethasone
  • Nitrogen