Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
, 58 (4), 381-7

Brain Shrinkage in Alcoholics: A Decade on and What Have We Learned?

Affiliations
Review

Brain Shrinkage in Alcoholics: A Decade on and What Have We Learned?

J J Kril et al. Prog Neurobiol.

Abstract

Brain atrophy in alcoholics has been identified using both radiological and pathological techniques. However the magnitude and topography of the atrophy, and the factors which contribute to it, are unclear. This review compares the results of imaging and pathological studies in alcoholics examining variables which may contribute to any discrepancies. We conclude that significant brain damage does occur as a result of alcohol abuse per se, that the damage is regionally specific with the frontal lobes being particularly affected, and that both grey matter and white matter components are damaged.

Similar articles

See all similar articles

Cited by 49 PubMed Central articles

See all "Cited by" articles

Publication types

LinkOut - more resources

Feedback