[The efficacy of Neovir in the combined treatment of patients with operable tumors of the gastrointestinal tract]

N I Glushkov; N V Shabashova; E V Frolova; A E Uchevatkina; K G Kubachev; V V Novakovskiĭ; V V Popkov

[The efficacy of Neovir in the combined treatment of patients with operable tumors of the gastrointestinal tract]

Vestn Khir Im I I Grek. 1999;158(2):59-61.

[Article in Russian]

Authors

N I Glushkov, N V Shabashova, E V Frolova, A E Uchevatkina, K G Kubachev, V V Novakovskiĭ, V V Popkov

PMID: 10368895

Abstract

Under observation there were 32 patients with operable tumors of the gastro-intestinal tract. The average age of the patients was (64.8 +/- 7.5) years. Patients of the control group (18 patients were given the routine complex treatment. The main group (14 patients) were additionally given the interferonogenic immunomodulator "Neovir" which resulted in lower risk of the appearance of pyo-septic complications. It was confirmed by positive dynamics of the indices of cellular immunity, intensified production of proinflammatory cytokines and interferon-alpha.

Publication types

Clinical Trial
Comparative Study
Controlled Clinical Trial
English Abstract

MeSH terms

Acridines / therapeutic use*
Adjuvants, Immunologic / therapeutic use*
Adult
Aged
Aged, 80 and over
Antibody Formation / drug effects
Chemotherapy, Adjuvant
Gastrointestinal Neoplasms / drug therapy*
Gastrointestinal Neoplasms / immunology
Gastrointestinal Neoplasms / surgery
Humans
Immunity, Cellular / drug effects
Interferon Inducers / therapeutic use*
Middle Aged
Postoperative Care
Preoperative Care
T-Lymphocytes / drug effects
T-Lymphocytes / immunology

Substances

Acridines
Adjuvants, Immunologic
Interferon Inducers
Camedon