Methods for defining and determining the clinical significance of treatment effects: description, application, and alternatives

N S Jacobson; L J Roberts; S B Berns; J B McGlinchey

doi:10.1037//0022-006x.67.3.300

Methods for defining and determining the clinical significance of treatment effects: description, application, and alternatives

J Consult Clin Psychol. 1999 Jun;67(3):300-7. doi: 10.1037//0022-006x.67.3.300.

Authors

N S Jacobson¹, L J Roberts, S B Berns, J B McGlinchey

Affiliation

¹ Department of Psychology, University of Washington, Seattle 98195, USA.

PMID: 10369050
DOI: 10.1037//0022-006x.67.3.300

Abstract

This article summarizes and scrutinizes the growth of the development of clinically relevant and psychometrically sound approaches for determining the clinical significance of treatment effects in mental health research by tracing its evolution, by examining modifications in the method, and by discussing representative applications. Future directions for this methodology are proposed.

Publication types

Research Support, U.S. Gov't, P.H.S.

MeSH terms

Clinical Trials as Topic / methods*
Clinical Trials as Topic / statistics & numerical data
Data Interpretation, Statistical
Evidence-Based Medicine / methods
Evidence-Based Medicine / statistics & numerical data
Humans
Normal Distribution
Outcome Assessment, Health Care / methods*
Outcome Assessment, Health Care / statistics & numerical data
Psychotherapy / standards*
Reference Values

Grants and funding

5KO2-MH00868-09/MH/NIMH NIH HHS/United States