Fat-free mass qualitative assessment with bioelectric impedance analysis (BIA)

Ann N Y Acad Sci. 1999 Apr 20;873:94-8. doi: 10.1111/j.1749-6632.1999.tb09454.x.


Body composition studies, when based on two-compartment volumetric estimates, can hardly assess nutritional states. Phase-sensitive impedance analysis can be used to reflect directly the proportions between intra- and extracellular spaces (ECM/BCM), which is one of the most sensitive indexes of malnutrition. Resistance and reactance values actually measured with BIA are referred to as the series RC model; however, due to the morphology of the FFM, which is composed of cells surrounded by interstitial fluids, in reality this should be modeled as a parallel RC circuit. A nomogram developed with series-to-parallel transformations of resistance and reactance measured with commercial BIA on controls and patients shows interesting gender and disease sensitivity and specificity.

MeSH terms

  • Anorexia Nervosa / physiopathology
  • Body Composition*
  • Body Mass Index*
  • Electric Impedance
  • Extracellular Space
  • Female
  • Humans
  • Male
  • Models, Biological
  • Nutrition Disorders / physiopathology
  • Renal Dialysis