[Amyloidosis. A review]

Ugeskr Laeger. 1999 May 24;161(21):3079-83.
[Article in Danish]

Abstract

Amyloidosis is a heterogenous group of diseases, all characterized by extracellular deposition of amyloid either systemically or localized. Of wellknown diseases are Alzheimer's dementia, AL-amyloidosis (e.g. in multiple myeloma) and AA-amyloidosis (e.g. in rheumatoid arthritis). Amyloid is composed of three components of which the fibrillary component is the basis of amyloid classification. Many types of amyloid have a systemic distribution and give rise to varying symptoms. The diagnosis is based on biopsy, preferably of abdominal subcutis. The prognosis is poor, however, recent investigations on the three-dimensional structure of the P-component provide hope for future therapy.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Amyloid / chemistry
  • Amyloid / classification
  • Amyloid / metabolism
  • Amyloidosis* / diagnosis
  • Amyloidosis* / metabolism
  • Amyloidosis* / pathology
  • Amyloidosis* / therapy
  • Humans
  • Prognosis

Substances

  • Amyloid