Bilirubin levels and severe retinopathy of prematurity in infants with estimated gestational ages of 23 to 26 weeks

J Pediatr. 1999 Jul;135(1):102-4. doi: 10.1016/s0022-3476(99)70336-7.


Oxidative injury may contribute to the development of retinopathy of prematurity (ROP), and bilirubin may be a physiologically important antioxidant. Therefore we evaluated the relationship of ROP to bilirubin levels in 157 infants born at 23 to 26 weeks estimated gestational age. We found no definite association between bilirubin levels and severe ROP.

Publication types

  • Comparative Study

MeSH terms

  • Analysis of Variance
  • Bilirubin / blood*
  • Female
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Logistic Models
  • Male
  • Odds Ratio
  • Retinopathy of Prematurity / blood*
  • Risk Factors
  • Severity of Illness Index


  • Bilirubin