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Review
, 11 (3), 363-71

hnRNP Complexes: Composition, Structure, and Function

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Review

hnRNP Complexes: Composition, Structure, and Function

A M Krecic et al. Curr Opin Cell Biol.

Abstract

Heterogeneous nuclear ribonucleoproteins (hnRNPs) are predominantly nuclear RNA-binding proteins that form complexes with RNA polymerase II transcripts. These proteins function in a staggering array of cellular activities, ranging from transcription and pre-mRNA processing in the nucleus to cytoplasmic mRNA translation and turnover. Recent studies suggest that several fundamental characteristics of hnRNPs account for their involvement in multiple regulatory pathways.

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