Abstract
The splicing of mRNA precursors (pre-mRNA) in the nucleus is catalyzed by a complex machinery termed the spliceosome. In order to understand how it functions in vivo, it is essential to complement biochemical analyses with a detailed study of how spliceosome components are organized within the nucleus.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Cell Nucleus / genetics
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Cell Nucleus / metabolism*
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Humans
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RNA Precursors / genetics
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RNA Precursors / metabolism*
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RNA Splicing*
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RNA, Small Nuclear / metabolism
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Spliceosomes / metabolism*
Substances
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RNA Precursors
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RNA, Small Nuclear