The role of somatic hypermutation in the generation of deletions and duplications in human Ig V region genes and chromosomal translocations

Curr Top Microbiol Immunol. 1999:246:193-8. doi: 10.1007/978-3-642-60162-0_24.

Authors

R Küppers¹, T Goossens, U Klein

Affiliation

¹ Institute for Genetics, University of Cologne, Germany. rkuppers@mac.genetik.uni-koeln.de

PMID: 10396056
DOI: 10.1007/978-3-642-60162-0_24

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

B-Lymphocytes / immunology
Gene Deletion
Gene Duplication
Genes, Immunoglobulin*
Germinal Center / cytology
Humans
Immunoglobulin Variable Region / genetics
Lymphoma, B-Cell / genetics
Lymphoma, B-Cell / immunology
Mutation*
Translocation, Genetic

Substances

Immunoglobulin Variable Region