Plasma lactate concentration as a predictor of gastric necrosis and survival among dogs with gastric dilatation-volvulus: 102 cases (1995-1998)

J Am Vet Med Assoc. 1999 Jul 1;215(1):49-52.


Objective: To determine relationships between plasma lactate concentration and gastric necrosis and between plasma lactate concentration and outcome for dogs with gastric dilatation-volvulus.

Design: Retrospective study.

Animals: 102 dogs.

Procedure: Information on signalment, history, plasma lactate concentration, medical and surgical treatment, cost of hospitalization, and outcome was retrieved from medical records.

Results: 69 of 70 (99%) dogs with plasma lactate concentration < 6.0 mmol/L survived, compared with 18 of 31 (58%) dogs with plasma lactate concentration > 6.0 mmol/L (1 dog euthanatized for economic reasons was not included). Gastric necrosis was identified in 38 (37%) dogs. Median plasma lactate concentration in dogs with gastric necrosis (6.6 mmol/L) was significantly higher than concentration in dogs without gastric necrosis (3.3 mmol/L). Specificity and sensitivity of using plasma lactate concentration (with a cutoff of 6.0 mmol/L) to predict which dogs had gastric necrosis were 88 and 61%, respectively. Sixty-two of 63 (98%) dogs without gastric necrosis survived, compared with 25 of 38 (66%) dogs with gastric necrosis.

Conclusions and clinical relevance: Preoperative plasma lactate concentration was a good predictor of gastric necrosis and outcome for dogs with GDV. Preoperative measurement of plasma lactate concentration may assist in determining prognosis of dogs with GDV.

MeSH terms

  • Animals
  • Dog Diseases / mortality
  • Dog Diseases / pathology*
  • Dog Diseases / surgery
  • Dogs
  • Female
  • Gastric Dilatation / mortality
  • Gastric Dilatation / pathology
  • Gastric Dilatation / veterinary*
  • Lactic Acid / blood*
  • Male
  • Necrosis
  • Predictive Value of Tests
  • Preoperative Care / veterinary
  • ROC Curve
  • Retrospective Studies
  • Stomach / pathology*
  • Stomach Volvulus / mortality
  • Stomach Volvulus / pathology
  • Stomach Volvulus / veterinary*
  • Survival Rate


  • Lactic Acid