Diffusion magnetic resonance imaging: its principle and applications

Anat Rec. 1999 Jun 15;257(3):102-9. doi: 10.1002/(SICI)1097-0185(19990615)257:3<102::AID-AR7>3.0.CO;2-6.


Diffusion magnetic resonance imaging (MRI) is one of the most rapidly evolving techniques in the MRI field. This method exploits the random diffusional motion of water molecules, which has intriguing properties depending on the physiological and anatomical environment of the organisms studied. We explain the principles of this emerging technique and subsequently introduce some of its present applications to neuroimaging, namely detection of ischemic stroke and reconstruction of axonal bundles and myelin fibers.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acute Disease
  • Brain / anatomy & histology
  • Brain / pathology
  • Cerebrovascular Disorders / diagnosis*
  • Humans
  • Magnetic Resonance Imaging / methods*