X-linked mental retardation associated with cleft lip/palate maps to Xp11.3-q21.3
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X-linked mental retardation associated with cleft lip/palate maps to Xp11.3-q21.3
Am J Med Genet.
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Abstract
A family is described in which X-linked mild to borderline mental retardation (MR) is associated with cleft lip/palate. Linkage analysis showed a maximum LOD score of Z=2.78 at straight theta=0.0 for the DXS441 locus with flanking markers DXS337 and DXS990, defining the region Xp11.3-q21.3 with a linkage interval of 25 cM.
Copyright 1999 Wiley-Liss, Inc.
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