[Use of the multifocal electroretinogram to evaluate retinal function after pars plana vitrectomy for diabetic macular edema]

Nippon Ganka Gakkai Zasshi. 1999 Jun;103(6):464-9.
[Article in Japanese]


Purpose: Multifocal electroretinograms (multifocal ERGs) were performed to evaluate retinal function in patients with diabetic macular edema.

Materials & methods: Eight eyes of 5 patients underwent pars plana vitrectomy for diabetic macular edema. Multifocal ERGs, fundus examinations, and fluorescent angiographies were done both before and after the operation.

Results: Post-operative visual acuity was improved by two or more lines in 3 eyes. In multifocal ERGs, the amplitude of the positive wave (P1) from the macular area decreased transiently after surgery (p < 0.05), but it improved with the passage of time. The P1 amplitude from the peripheral area was decreased throughout the observation period of six months (p < 0.05). For both areas, the P1 latency was increased significantly (p < 0.05) at one month post-operatively, and then decreased.

Conclusion: These findings are consistent with the possibility that the surgical method, especially removal of the posterior cortical vitreous, can cause retinal damage.

Publication types

  • English Abstract

MeSH terms

  • Diabetic Retinopathy / physiopathology*
  • Diabetic Retinopathy / surgery*
  • Edema / physiopathology*
  • Edema / surgery*
  • Electroretinography* / methods
  • Female
  • Humans
  • Male
  • Middle Aged
  • Vitrectomy*