Measuring cerebral blood flow using magnetic resonance imaging techniques

J Cereb Blood Flow Metab. 1999 Jul;19(7):701-35. doi: 10.1097/00004647-199907000-00001.


Magnetic resonance imaging techniques measuring CBF have developed rapidly in the last decade, resulting in a wide range of available methods. The most successful approaches are based either on dynamic tracking of a bolus of a paramagnetic contrast agent (dynamic susceptibility contrast) or on arterial spin labeling. This review discusses their principles, possible pitfalls, and potential for absolute quantification and outlines clinical and neuroscientific applications.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cerebrovascular Circulation*
  • Humans
  • Magnetic Resonance Imaging* / methods