Interaction between stromal cells and tumor cells induces chemoresistance and matrix metalloproteinase secretion

Ann N Y Acad Sci. 1999 Jun 30;878:642-6. doi: 10.1111/j.1749-6632.1999.tb07750.x.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Coculture Techniques
  • Collagenases / biosynthesis
  • Drug Resistance, Neoplasm*
  • Endothelium, Vascular / cytology
  • Endothelium, Vascular / physiology
  • Epithelial Cells / cytology
  • Epithelial Cells / physiology
  • Gelatinases / biosynthesis
  • Humans
  • Male
  • Matrix Metalloproteinase 2
  • Matrix Metalloproteinase 9
  • Metalloendopeptidases / biosynthesis*
  • Microcirculation
  • Paclitaxel / toxicity*
  • Prostatic Neoplasms / pathology
  • Prostatic Neoplasms / physiopathology*
  • Protease Inhibitors / toxicity*
  • Rats
  • Stromal Cells / cytology
  • Stromal Cells / physiology*
  • Tetracyclines / toxicity*
  • Tumor Cells, Cultured

Substances

  • Protease Inhibitors
  • Tetracyclines
  • tetracycline CMT-3
  • Collagenases
  • Gelatinases
  • Metalloendopeptidases
  • Matrix Metalloproteinase 2
  • Matrix Metalloproteinase 9
  • Paclitaxel