Visualization of magnetoencephalographic data using minimum current estimates

Neuroimage. 1999 Aug;10(2):173-80. doi: 10.1006/nimg.1999.0454.


The locations of active brain areas can be estimated from the magnetic field the neural current sources produce. In this work we study a visualization method of magnetoencephalographic data that is based on minimum[symbol: see text] (1)-norm estimates. The method can represent several local or distributed sources and does not need explicit a priori information. We evaluated the performance of the method using simulation studies. In a situation resembling typical magnetoencephalographic measurement, the mean estimated source strength exceeded baseline level up to 2 cm from the simulated point-like source. The method can also visualize several sources, activated simultaneously or in a sequence, which we demonstrated by analyzing magnetic responses associated with sensory stimulation and a picture naming task.

MeSH terms

  • Algorithms
  • Arousal / physiology
  • Attention / physiology
  • Brain / anatomy & histology
  • Brain / physiology
  • Brain Mapping / instrumentation
  • Computer Simulation
  • Data Interpretation, Statistical*
  • Humans
  • Image Processing, Computer-Assisted / instrumentation*
  • Linear Models*
  • Magnetoencephalography / instrumentation*
  • Magnetoencephalography / statistics & numerical data
  • Reference Values