A new D-type cyclin of Arabidopsis thaliana expressed during lateral root primordia formation

Planta. 1999 Jun;208(4):453-62. doi: 10.1007/s004250050582.


D-type cyclins are believed to regulate the onset of cell division upon mitogenic signaling. Here, the isolation is reported of a new D-type cyclin gene (CYCD4;1) of Arabidopsis thaliana (L.) Heynh. during a two-hybrid screen using the cyclin-dependent kinase CDC2aAt as bait. Transcription of CYCD4;1 can be induced by sucrose. The co-regulated expression of CYCD4;1 and CDC2aAt in starved suspension cultures upon mitogenic stimulation indicates that the formation of a complex between these two partners is important for the resumption of cell division activity. By in-situ hybridizations CYCD4;1 was shown to be expressed during vascular tissue development, embryogenesis, and formation of lateral root primordia. Expression during the latter process suggests that the induced expression of D-type cyclins by mitogenic stimuli might be one of the rate-limiting events for the initiation of lateral roots.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Arabidopsis / metabolism*
  • Base Sequence
  • Cyclin D
  • Cyclins / genetics*
  • DNA, Complementary
  • Molecular Sequence Data
  • Sequence Homology, Amino Acid


  • Cyclin D
  • Cyclins
  • DNA, Complementary