Microchimerism in Japanese women patients with systemic sclerosis

Lancet. 1999 Jul 17;354(9174):220. doi: 10.1016/S0140-6736(99)00164-6.


To examine whether microchimerism occurs in Japanese women patients with systemic sclerosis, we analysed the Y-chromosome in DNA by PCR. There was no significant difference between patients and healthy people, suggesting that microchimerism may not be the sole pathogenesis in Japanese women with systemic sclerosis.

Publication types

  • Letter

MeSH terms

  • Chimera
  • Female
  • Humans
  • Japan
  • Male
  • Mosaicism*
  • Polymerase Chain Reaction
  • Scleroderma, Systemic / genetics*
  • Y Chromosome