Telomeric (TTAGGG)n Sequences Are Associated With Nucleolus Organizer Regions (NORs) in the Wood Lemming

Chromosome Res. 1999;7(3):235-40. doi: 10.1023/a:1009255517764.

Abstract

The distribution of the (TTAGGG)n telomeric sequence was studied in chromosomes of the wood lemming, Myopus schisticolor, by fluorescence in-situ hybridization. As expected, the hybridization signals were observed at telomeres of all chromosomes. However, quite a number of interstitial telomeric sites were present in the pericentric heterochromatic regions. Consistent strong hybridization signals were also seen at one terminus of chromosomes 5, 7 and 12--15. By post-hybridization G-banding and silver-staining, the large blocks of the telomeric sequences on chromosomes 5 and 12 were localized to nucleolus organizer regions (NORs).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Arvicolinae / genetics*
  • Base Sequence
  • Chromosome Banding
  • In Situ Hybridization, Fluorescence
  • Nucleolus Organizer Region / genetics*
  • Telomere / genetics*