Anticipating epileptic seizures in real time by a non-linear analysis of similarity between EEG recordings

Neuroreport. 1999 Jul 13;10(10):2149-55. doi: 10.1097/00001756-199907130-00028.

Abstract

In a previous publication we showed that non-linear analysis can extract spatio-temporal changes of brain electrical activity prior to epileptic seizures. Here we describe a new method to analyze this long-term non-stationarity in the EEG by a measure of dynamical similarity between different parts of the time series. We apply this method to the study of a group of patients with temporal lobe epilepsy recorded intracranially during transitions to seizure. We show that the method, which can be implemented on a personal computer, can track in real time spatio-temporal changes in brain dynamics several minutes prior to seizure.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Computer Systems*
  • Electroencephalography*
  • Epilepsy, Temporal Lobe / physiopathology*
  • Humans
  • Nonlinear Dynamics
  • Predictive Value of Tests
  • Video Recording