Inverse association between breast cancer incidence and degree of visual impairment in Finland

Br J Cancer. 1999 Jul;80(9):1459-60. doi: 10.1038/sj.bjc.6690544.


A total of 10935 women with visual impairment were identified from the Finnish Register of Visual Impairment and followed up for cancer through the Finnish Cancer Registry for years 1983-1996. Breast cancer risk decreased by degree of visual impairment (P for trend 0.04) which suggests a dose-response relationship between visible light and breast cancer risk.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Breast Neoplasms / epidemiology*
  • Breast Neoplasms / prevention & control
  • Female
  • Finland / epidemiology
  • Humans
  • Incidence
  • Melatonin / physiology
  • Middle Aged
  • Vision Disorders / physiopathology*


  • Melatonin