Src autoinhibition: let us count the ways

Nat Struct Biol. 1999 Aug;6(8):711-4. doi: 10.1038/11468.


Src family tyrosine kinases are key cellular signaling enzymes whose catalytic activities are tightly controlled. Recent structural and mutational studies have revealed additional intricacies in the autoinhibitory mechanisms by which catalytic activity is repressed.

Publication types

  • News

MeSH terms

  • Catalysis
  • Enzyme Activation
  • Models, Molecular
  • src Homology Domains
  • src-Family Kinases / antagonists & inhibitors*
  • src-Family Kinases / chemistry
  • src-Family Kinases / metabolism


  • src-Family Kinases