Amyloid arthropathy in chickens

Vet Q. 1999 Jun;21(3):78-82. doi: 10.1080/01652176.1999.9694998.

Abstract

The present paper presents an overview of current knowledge of amyloid arthropathy in chickens, and covers the pathogenesis of amyloidosis in general and in birds, field cases reported, and the studies performed to assess the amyloidogenicity of various agents compared to that of Enterococcus faecalis. An animal model of amyloid arthropathy is presented, as are studies on the pathogenesis of arthropathic and amyloidogenic E. faecalis infections in brown layers. The review concludes with a description of the pathology of amyloid arthropathy, the biochemical characterization of the chicken joint amyloid protein as being of the AA type, investigation of the serum amyloid A (SAA) gene involved, and local SAA mRNA expression in joint and liver.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Academic Dissertations as Topic
  • Amyloidosis / etiology
  • Amyloidosis / metabolism
  • Amyloidosis / microbiology
  • Amyloidosis / veterinary*
  • Animals
  • Arthritis / etiology
  • Arthritis / metabolism
  • Arthritis / microbiology
  • Arthritis / veterinary*
  • Chickens
  • Disease Models, Animal
  • Enterococcus faecalis / pathogenicity
  • Liver / metabolism
  • Poultry Diseases / etiology*
  • Poultry Diseases / metabolism
  • Poultry Diseases / microbiology
  • RNA, Messenger / biosynthesis
  • Serum Amyloid A Protein / analysis
  • Serum Amyloid A Protein / genetics
  • Serum Amyloid A Protein / metabolism
  • Synovial Membrane / metabolism

Substances

  • RNA, Messenger
  • Serum Amyloid A Protein