Review
doi: 10.1016/s0968-0004(99)01426-7.
The ankyrin repeat: a diversity of interactions on a common structural framework
Affiliations
- PMID: 10431175
- DOI: 10.1016/s0968-0004(99)01426-7
Item in Clipboard
Review
The ankyrin repeat: a diversity of interactions on a common structural framework
Trends Biochem Sci.
1999 Aug.
Abstract
The ankyrin repeat is one of the most common protein sequence motifs. Recent X-ray and NMR structures of ankyrin-repeat proteins and their complexes have provided invaluable insights into the molecular basis of the extraordinary variety of biological activities of these molecules. In particular, they have begun to reveal how a large family of structurally related proteins can interact specifically with such a diverse array of macromolecular targets.
Similar articles
-
The membrane-binding domain of ankyrin contains four independently folded subdomains, each comprised of six ankyrin repeats.J Biol Chem. 1993 Oct 25;268(30):22703-9. J Biol Chem. 1993. PMID: 8226780
-
Identifying tandem Ankyrin repeats in protein structures.BMC Bioinformatics. 2014 Dec 30;15(1):6599. doi: 10.1186/s12859-014-0440-9. BMC Bioinformatics. 2014. PMID: 25547411 Free PMC article.
-
Structural basis of diverse membrane target recognitions by ankyrins.Elife. 2014 Nov 10;3:e04353. doi: 10.7554/eLife.04353. Elife. 2014. PMID: 25383926 Free PMC article.
-
Ankyrins, multifunctional proteins involved in many cellular pathways.Folia Histochem Cytobiol. 2002;40(3):239-49. Folia Histochem Cytobiol. 2002. PMID: 12219834 Review.
-
Folding landscapes of ankyrin repeat proteins: experiments meet theory.Curr Opin Struct Biol. 2008 Feb;18(1):27-34. doi: 10.1016/j.sbi.2007.12.004. Curr Opin Struct Biol. 2008. PMID: 18243686 Free PMC article. Review.
Cited by
-
TCR mimic compounds for pHLA targeting with high potency modalities in oncology.Front Oncol. 2022 Oct 21;12:1027548. doi: 10.3389/fonc.2022.1027548. eCollection 2022. Front Oncol. 2022. PMID: 36338746 Free PMC article. Review.
-
CCCH-type zinc finger family in maize: genome-wide identification, classification and expression profiling under abscisic acid and drought treatments.PLoS One. 2012;7(7):e40120. doi: 10.1371/journal.pone.0040120. Epub 2012 Jul 6. PLoS One. 2012. PMID: 22792223 Free PMC article.
-
Prokaryotic expression of antibodies and affibodies.Curr Opin Biotechnol. 2004 Aug;15(4):364-73. doi: 10.1016/j.copbio.2004.06.004. Curr Opin Biotechnol. 2004. PMID: 15296932 Free PMC article. Review.
-
Analysis of ankyrin repeats reveals how a single point mutation in RFXANK results in bare lymphocyte syndrome.Mol Cell Biol. 2001 Aug;21(16):5566-76. doi: 10.1128/MCB.21.16.5566-5576.2001. Mol Cell Biol. 2001. PMID: 11463838 Free PMC article.
-
A Systematical Survey on the TRP Channels Provides New Insight into Its Functional Diversity in Zhikong Scallop (Chlamys farreri).Int J Mol Sci. 2021 Oct 14;22(20):11075. doi: 10.3390/ijms222011075. Int J Mol Sci. 2021. PMID: 34681735 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases
