Regulatory networks controlling Candida albicans morphogenesis

Trends Microbiol. 1999 Aug;7(8):333-8. doi: 10.1016/s0966-842x(99)01556-5.


Candida albicans undergoes reversible morphogenetic transitions between budding, pseudohyphal and hyphal growth forms that promote the virulence of this pathogenic fungus. The regulatory networks that control morphogenesis are being elucidated; however, the primary signals that trigger morphogenesis remain obscure, and the physiological outputs of these networks are complex.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Candida albicans / cytology
  • Candida albicans / genetics
  • Candida albicans / growth & development*
  • Candida albicans / pathogenicity
  • Candidiasis / microbiology
  • Fungal Proteins / metabolism
  • Gene Expression Regulation, Fungal
  • Humans
  • Mice
  • Morphogenesis
  • Signal Transduction


  • Fungal Proteins