Regulatory Networks Controlling Candida Albicans Morphogenesis

Trends Microbiol. 1999 Aug;7(8):333-8. doi: 10.1016/s0966-842x(99)01556-5.

Abstract

Candida albicans undergoes reversible morphogenetic transitions between budding, pseudohyphal and hyphal growth forms that promote the virulence of this pathogenic fungus. The regulatory networks that control morphogenesis are being elucidated; however, the primary signals that trigger morphogenesis remain obscure, and the physiological outputs of these networks are complex.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Candida albicans / cytology
  • Candida albicans / genetics
  • Candida albicans / growth & development*
  • Candida albicans / pathogenicity
  • Candidiasis / microbiology
  • Fungal Proteins / metabolism
  • Gene Expression Regulation, Fungal
  • Humans
  • Mice
  • Morphogenesis
  • Signal Transduction

Substances

  • Fungal Proteins