Course of postoperative inflammation after implantation of 4 types of foldable intraocular lenses

J Cataract Refract Surg. 1999 Aug;25(8):1116-20. doi: 10.1016/s0886-3350(99)00134-0.

Abstract

Purpose: To compare the course of postoperative inflammation after small incision cataract surgery with implantation of 4 types of foldable intraocular lenses (IOLs).

Setting: Department of Ophthalmology, University Hospital of Vienna, Austria.

Methods: One hundred twenty eyes were prospectively randomized to receive a foldable silicone (Pharmacia 920), hydrogel (Bausch & Lomb Hydroview), methyl methacrylate/hydroxyethyl methacrylate (Mentor MemoryLens), or acrylic (Alcon AcrySof) IOL. All surgery was performed by the same experienced surgeon using a standardized surgical protocol: clear corneal incision, capsulorhexis, phacoemulsification, and in-the-bag implantation of the IOL. All patients received standardized postoperative medication and follow-up. Postoperative inflammation was evaluated by measuring aqueous flare preoperatively and 1, 3, 7, 14, 28, 90, and 180 days after surgery using the Kowa 1000 laser flare-cell meter.

Results: Except on the first day after surgery, when the AcrySof group had higher flare values than the other groups (P = .0265), no significant differences were found up to 6 months. Re-establishment of the blood-aqueous barrier was similar in eyes with the AcrySof, Hydroview, and MemoryLens IOLs; the course of postoperative inflammation was different in eyes with the silicone IOL.

Conclusion: Comparison of postoperative flare values after implantation of 4 foldable IOLs showed no clinically relevant differences in the course of postoperative inflammation.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Acrylic Resins
  • Aged
  • Blood-Aqueous Barrier
  • Female
  • Foreign-Body Reaction / etiology*
  • Foreign-Body Reaction / physiopathology
  • Humans
  • Hydrogel, Polyethylene Glycol Dimethacrylate
  • Lens Implantation, Intraocular*
  • Lenses, Intraocular / adverse effects*
  • Male
  • Polymethyl Methacrylate
  • Postoperative Complications / physiopathology
  • Prospective Studies
  • Silicone Elastomers
  • Time Factors
  • Uveitis, Anterior / etiology*
  • Uveitis, Anterior / physiopathology

Substances

  • Acrylic Resins
  • Silicone Elastomers
  • Hydrogel, Polyethylene Glycol Dimethacrylate
  • Polymethyl Methacrylate