Onset of sucrase-isomaltase deficiency in late adulthood

Am J Gastroenterol. 1999 Aug;94(8):2298-9. doi: 10.1111/j.1572-0241.1999.01320.x.


Sucrase-isomaltase deficiency is a rare disorder usually manifested as diarrhea in infancy. The presentation of such a deficiency in adulthood is even more rare, particularly when the individual has no history of childhood diarrhea. After a literature search, the 59-yr-old patient we report is the oldest to have been identified with this condition. The difficulties encountered in diagnosis when such a case occurs at this age that have not previously been reported are highlighted.

Publication types

  • Case Reports

MeSH terms

  • Carbohydrate Metabolism, Inborn Errors / diagnosis*
  • Carbohydrate Metabolism, Inborn Errors / genetics
  • Diagnosis, Differential
  • Diarrhea / diet therapy
  • Diarrhea / etiology
  • Dietary Carbohydrates / administration & dosage
  • Duodenum / enzymology
  • Humans
  • Male
  • Middle Aged
  • Sucrase-Isomaltase Complex / deficiency*
  • Sucrase-Isomaltase Complex / genetics


  • Dietary Carbohydrates
  • Sucrase-Isomaltase Complex