Plant-based production of xenogenic proteins

Curr Opin Biotechnol. 1999 Aug;10(4):382-6. doi: 10.1016/S0958-1669(99)80069-X.


Foreign protein production in transgenic plants has been successful, from the generation of transgenic plant lines to the marketing of purified proteins. Antigenic proteins from disease organisms, monoclonal antibodies raised against antigens of disease organisms, and proteins with industrial process applications have been produced and tested. For vaccines, clinical trials in humans and feeding trials in animals are in progress to demonstrate their efficacy. For industrial proteins, high expression and downstream processing efficiency are key concerns, with application and test market trials in progress.

Publication types

  • Review

MeSH terms

  • Animals
  • Antibody Formation / genetics
  • Biotechnology
  • Enzymes / biosynthesis
  • Enzymes / genetics
  • Humans
  • Plants, Genetically Modified / genetics*
  • Protein Engineering
  • Recombinant Proteins / biosynthesis*
  • Recombinant Proteins / genetics*
  • Recombinant Proteins / isolation & purification
  • Vaccines, Synthetic / biosynthesis
  • Vaccines, Synthetic / genetics


  • Enzymes
  • Recombinant Proteins
  • Vaccines, Synthetic