Inwardly rectifying potassium channels

Curr Opin Cell Biol. 1999 Aug;11(4):503-8. doi: 10.1016/S0955-0674(99)80073-8.

Abstract

Inwardly rectifying potassium (Kir) channels regulate the resting membrane potential of the cell and thereby modulate the electrical activity of cardiac and neuronal cells, insulin secretion and epithelial K(+) transport. Considerable progress in understanding the molecular structure of Kir channels and the way in which they are regulated by extracellular and intracellular modulators has been made during the past year.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Bartter Syndrome / genetics
  • Humans
  • Hyperinsulinism / genetics
  • Hypoglycemia / genetics
  • Potassium Channels / chemistry
  • Potassium Channels / genetics
  • Potassium Channels / metabolism
  • Potassium Channels / physiology*
  • Potassium Channels, Inwardly Rectifying*
  • Protein Conformation

Substances

  • Potassium Channels
  • Potassium Channels, Inwardly Rectifying