Histopathologic study of presumed parafoveal telangiectasis

Retina. 1999;19(4):332-5. doi: 10.1097/00006982-199907000-00011.

Abstract

Purpose: To report the postmortem histopathologic features that closely resemble the clinical features of parafoveal telangiectasis.

Methods: Light and electron microscopy.

Results: Histopathologic features included macular edema; telangiectatic vessels; retinal, subretinal, and superficial retinal neovascularization; retinal pigment epithelial hyperplasia around neovascular aggregates; retinal-choroidal vascular anastomosis; and superficial pigmented cells with lipofuscin.

Conclusion: The postmortem histopathologic findings in a 36-year-old woman with Down syndrome and other systemic conditions correlate with features noted in previous reports of presumed parafoveal telangiectasis.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Arterio-Arterial Fistula / etiology
  • Arterio-Arterial Fistula / pathology
  • Choroid / blood supply
  • Choroid / ultrastructure
  • Down Syndrome / complications
  • Fatal Outcome
  • Female
  • Fovea Centralis / blood supply*
  • Fovea Centralis / ultrastructure
  • Humans
  • Macular Edema / etiology
  • Macular Edema / pathology
  • Retinal Artery / abnormalities
  • Retinal Diseases / etiology
  • Retinal Diseases / pathology*
  • Retinal Neovascularization / etiology
  • Retinal Neovascularization / pathology
  • Telangiectasis / complications
  • Telangiectasis / pathology*