The comparison of cyclopentolate and atropine in patients with refractive accommodative esotropia by means of retinoscopy, autorefractometry and biometric lens thickness

Acta Ophthalmol Scand. 1999 Aug;77(4):426-9. doi: 10.1034/j.1600-0420.1999.770414.x.

Abstract

Purpose: In this study, we aimed to compare the cycloplegic effect of cyclopentolate HCI 1% and atropine sulphate 1% in patients with refractive accommodative esotropia by means of retinoscopy, autorefractometer and the measurement of lens thickness by biometry.

Methods: Thirty-two patients with refractive accommodative esotropia aged from 5 to 10 (mean 6.8+/-1.4), had a deviation under 10 prism diopters, and underwent retinoscopic, autorefractometric and biometric study in dry and wet conditions.

Results: The retinoscopic, autorefractometric and biometric findings of the right eye were 5.10+/-1.21 diopter (D), 5.03+/-1.20 D, 3.43+/-0.16 mm with cyclopentolate, and 5.2+/-1.2 D, 5.2+/-1.2 D, 3.4+/-0.1 mm with atropine. In the left eye, the measurements were 5.2+/-1.4 D, 5.1+/-1.4 D, 3.5+/-0.2 mm with cyclopentolate, and 5.3+/-1.2 D, 5.20+/-1.3 D, 3.4+/-0.2 mm with atropine, respectively. When these obtained data were compared by the Student's t test no statistical significance was found (p > 0.05).

Conclusions: We suggest that the cyclopentolate cycloplegia applied to the patients with refractive accommodative esotropia is sufficient to produce good cycloplegia, with an effect similar to atropine.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Accommodation, Ocular / drug effects*
  • Atropine / administration & dosage
  • Atropine / therapeutic use*
  • Child
  • Child, Preschool
  • Cyclopentolate / administration & dosage
  • Cyclopentolate / therapeutic use*
  • Esotropia / diagnosis
  • Esotropia / drug therapy*
  • Esotropia / physiopathology
  • Female
  • Follow-Up Studies
  • Humans
  • Lens, Crystalline / drug effects
  • Lens, Crystalline / pathology*
  • Male
  • Mydriatics / administration & dosage
  • Mydriatics / therapeutic use*
  • Ophthalmic Solutions
  • Pupil / drug effects
  • Refraction, Ocular / drug effects*
  • Visual Acuity

Substances

  • Mydriatics
  • Ophthalmic Solutions
  • Atropine
  • Cyclopentolate