Massive disseminated intravascular coagulation and hyperfibrinolysis in alveolar rhabdomyosarcoma: case report and review of the literature

Ann Hematol. 1999 Jul;78(7):335-8. doi: 10.1007/s002770050525.


A 68-year-old woman presented with profuse hemorrhage and other signs suggesting an acute leukemia. Histologic and cytogenetic evaluation of her bone marrow revealed alveolar rhabdomyosarcoma as the underlying cause of massive disseminated intravascular coagulation and hyperfibrinolysis. A review of the literature reveals that coagulopathy appears to be a common feature of alveolar rhabdomyosarcoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Disseminated Intravascular Coagulation / complications*
  • Female
  • Fibrinolysis*
  • Humans
  • Rhabdomyosarcoma, Alveolar / complications*