Abstract
The endoplasmic reticulum ensures proper folding of secretory proteins. In this review, we summarize and discuss the functions of different classes of folding mediators in the secretory pathway and propose updated models of the quality control system.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Cell Compartmentation
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Endoplasmic Reticulum / metabolism*
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Glycoproteins / metabolism
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Lectins / metabolism
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Peptidylprolyl Isomerase / metabolism
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Protein Disulfide-Isomerases / metabolism
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Protein Folding*
Substances
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Glycoproteins
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Lectins
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Peptidylprolyl Isomerase
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Protein Disulfide-Isomerases