Erythema elevatum diutinum and HIV infection: a report of five cases

Br J Dermatol. 1999 Aug;141(2):335-8. doi: 10.1046/j.1365-2133.1999.02988.x.


Erythema elevatum diutinum (EED) is emerging as a specific HIV-associated dermatosis, 11 cases having so far been reported in the medical literature and five patients with the disease having been seen by us during the last 4 years. As the disease is poorly known, it is easily confused with Kaposi's sarcoma or bacillary angiomatosis, but the histopathological features are diagnostic. EED is considered to be an immune complex-mediated vasculitis. A streptococcal infection seemed to be the trigger factor in four of our patients. Partial control of the cutaneous lesions was achieved by the use of antibiotics.

MeSH terms

  • AIDS-Related Opportunistic Infections / complications
  • AIDS-Related Opportunistic Infections / pathology
  • Adult
  • Angiomatosis, Bacillary / diagnosis
  • Anti-Bacterial Agents / therapeutic use
  • Diagnosis, Differential
  • Erythema / complications
  • Erythema / pathology
  • Erythema / virology*
  • Female
  • HIV Infections / complications*
  • Humans
  • Male
  • Sarcoma, Kaposi / diagnosis
  • Streptococcal Infections / complications
  • Streptococcal Infections / drug therapy
  • Vasculitis / complications


  • Anti-Bacterial Agents