Abstract
A mitotic checkpoint arrests cell cycle progression in response to spindle damage. It now appears that this checkpoint has two separate arms, one that prevents anaphase and a second that prevents cytokinesis and DNA re-replication.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Anaphase / physiology
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Animals
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Calcium-Binding Proteins / physiology
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Carrier Proteins*
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Cell Cycle / physiology
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Cell Cycle Proteins*
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Cell Division / physiology
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Chromosomes / physiology*
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Chromosomes, Fungal / physiology
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DNA Replication
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Fungal Proteins / physiology
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Kinetochores / physiology
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Mad2 Proteins
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Mitosis / physiology*
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Models, Biological
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Nuclear Proteins
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Saccharomyces cerevisiae / cytology
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Saccharomyces cerevisiae / physiology
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Saccharomyces cerevisiae Proteins*
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Spindle Apparatus / physiology
Substances
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BUB2 protein, S cerevisiae
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Calcium-Binding Proteins
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Carrier Proteins
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Cell Cycle Proteins
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Fungal Proteins
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MAD2 protein, S cerevisiae
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Mad2 Proteins
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Nuclear Proteins
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Saccharomyces cerevisiae Proteins