Sinonasal lymphoma

Otolaryngol Head Neck Surg. 1999 Sep;121(3):323-6. doi: 10.1016/S0194-5998(99)70192-0.


The clinical course of 49 patients with the diagnosis of non-Hodgkin's lymphoma were studied in the Department of Otolaryngology of the Hospital General de Mexico between December 1986 and March 1997. The most frequent clinical symptoms in these patients were: nasal obstruction, rhinorrhea, fever, weight loss, cervical lymph adenopathy, rhinopharyngeal tumor, ulceration on the palate and periorbital cellulitis. In 73% of the patients in this series the primary presentation was nasal. Sixty-six percent of the patients were classified as intermediate grade lymphoma according to the New Working Formulation, and 33% were in a I B state according to the Ann Arbor predominant immunotype was B cell in 63% of the cases. An extensive review of the literature is also presented.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Female
  • Humans
  • Lymphoma, Non-Hodgkin* / complications
  • Lymphoma, Non-Hodgkin* / diagnosis
  • Lymphoma, Non-Hodgkin* / pathology
  • Male
  • Middle Aged
  • Nose Neoplasms* / complications
  • Nose Neoplasms* / diagnosis
  • Nose Neoplasms* / pathology
  • Paranasal Sinus Neoplasms* / complications
  • Paranasal Sinus Neoplasms* / diagnosis
  • Paranasal Sinus Neoplasms* / pathology
  • Retrospective Studies