End-stage renal failure patients on long-term renal dialysis who underwent total hip arthroplasty (THA) were followed. Fifteen hips were implanted in 12 patients. There was a high mortality (58%) and high overall early complication rate (58%) with a deep infection rate of 13%. Of patients, 76% (n = 11) had good clinicoradiologic outcome of the THA before their death or at their latest follow-up. THA in patients on dialysis, however, should be reserved for those among this group who are expected to have a better life expectancy.