Pseudophakic cystoid macular edema treated with high-dose intravenous methylprednisolone

J Cataract Refract Surg. 1999 Sep;25(9):1286-8. doi: 10.1016/s0886-3350(99)00159-5.

Abstract

Purpose: To evaluate the efficacy of high-dose methylprednisolone in the treatment of pseudophakic cystoid macular edema (CME).

Setting: University-affiliated hospital.

Methods: Four patients with pseudophakic CME who reported decreased visual acuities were treated with oral prednisolone (20 mg daily for 5 days), oral acetazolamide (500 mg daily for 5 days), and topical dexamethasone 0.1% and diclofenac 0.1% (4 times a day for 14 days). The CME did not resolve. Next, they were treated with high-dose (1000 mg daily) intravenous methylprednisolone for 3 days.

Results: In 3 of 4 eyes, the CME resolved and visual acuity improved.

Conclusion: High-dose methylprednisolone may be effective in the treatment of pseudophakic CME.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cataract Extraction / adverse effects
  • Female
  • Fluorescein Angiography
  • Fundus Oculi
  • Glucocorticoids / administration & dosage
  • Glucocorticoids / therapeutic use*
  • Humans
  • Infusions, Intravenous
  • Macular Edema / drug therapy*
  • Macular Edema / etiology
  • Macular Edema / pathology
  • Male
  • Methylprednisolone / administration & dosage
  • Methylprednisolone / therapeutic use*
  • Middle Aged
  • Pseudophakia / drug therapy*
  • Pseudophakia / etiology
  • Pseudophakia / pathology
  • Visual Acuity / drug effects

Substances

  • Glucocorticoids
  • Methylprednisolone