Purpose: To evaluate the efficacy of high-dose methylprednisolone in the treatment of pseudophakic cystoid macular edema (CME).
Setting: University-affiliated hospital.
Methods: Four patients with pseudophakic CME who reported decreased visual acuities were treated with oral prednisolone (20 mg daily for 5 days), oral acetazolamide (500 mg daily for 5 days), and topical dexamethasone 0.1% and diclofenac 0.1% (4 times a day for 14 days). The CME did not resolve. Next, they were treated with high-dose (1000 mg daily) intravenous methylprednisolone for 3 days.
Results: In 3 of 4 eyes, the CME resolved and visual acuity improved.
Conclusion: High-dose methylprednisolone may be effective in the treatment of pseudophakic CME.