Hematologic side effects of psychotropics

Psychosomatics. Sep-Oct 1999;40(5):414-21. doi: 10.1016/S0033-3182(99)71206-5.


Psychiatrists are often unaware of the potential hematologic complications of the psychotropics they prescribe. Although this review is not a hematologic text reference, relevant hematologic syndromes are described so that the consultation-liaison psychiatrist will be familiar with the usual signs, symptoms, and treatments of these syndromes. This article reviews the hematologic side effects of the commonly prescribed psychotropics, including antipsychotics, antidepressants, benzodiazepines, lithium, mood stabilizers (including some of the anticonvulsants), and the acetylcholinesterase inhibitors. Clinical signs and symptoms that should alert the physician to obtain a complete blood count are described.

Publication types

  • Review

MeSH terms

  • Blood Cell Count / drug effects
  • Drug Monitoring
  • Hematologic Diseases / blood
  • Hematologic Diseases / chemically induced*
  • Humans
  • Psychotropic Drugs / adverse effects*
  • Psychotropic Drugs / blood


  • Psychotropic Drugs