Laser-guided direct writing for applications in biotechnology

Trends Biotechnol. 1999 Oct;17(10):385-9. doi: 10.1016/s0167-7799(99)01355-4.


Laser-induced optical forces can be used to guide and deposit 100 nm - 10 microm-diameter particles onto solid surfaces in a process we call 'laser-guided direct writing'. Nearly any particulate material, including both biological and electronic materials, can be manipulated and deposited on surfaces with micrometer accuracy. Potential applications include three-dimensional cell patterning for tissue engineering, hybrid biological-electronic-device construction, and biochip-array fabrication.

MeSH terms

  • Artificial Organs
  • Biotechnology / methods*
  • Electronics
  • Lasers*
  • Optics and Photonics