Narcolepsy: a key role for hypocretins (orexins)

MeSH terms

• Animals
• Appetite / physiology
• Arousal / physiology
• Calcium Signaling
• Carrier Proteins / genetics
• Carrier Proteins / metabolism
• Carrier Proteins / physiology*
• Cataplexy / genetics
• Cataplexy / metabolism
• Chromosomes, Human, Pair 17 / genetics
• Dog Diseases / genetics
• Dogs
• Genes, Recessive
• Genetic Predisposition to Disease
• HLA-DQ Antigens / genetics
• HLA-DQ beta-Chains
• Humans
• Hypothalamus / metabolism
• Hypothalamus / physiopathology
• Intracellular Signaling Peptides and Proteins*
• Limbic System / physiopathology
• Locus Coeruleus / physiopathology
• Mice
• Mice, Knockout
• Narcolepsy / genetics
• Narcolepsy / metabolism*
• Narcolepsy / veterinary
• Nerve Degeneration / genetics
• Neuropeptides / deficiency
• Neuropeptides / genetics
• Neuropeptides / metabolism
• Neuropeptides / physiology*
• Orexin Receptors
• Orexins
• Rats
• Receptors, G-Protein-Coupled
• Receptors, Neuropeptide / deficiency*
• Receptors, Neuropeptide / genetics
• Receptors, Neuropeptide / physiology
• Sequence Deletion
• Sleep / physiology
• gamma-Aminobutyric Acid / physiology