Hyphema associated with pupillary dilation in a patient with exfoliation glaucoma and warfarin therapy

Am J Ophthalmol. 1999 Jul;128(1):98-100. doi: 10.1016/s0002-9394(99)00024-0.

Abstract

Purpose: To describe an unusual hemorrhagic complication associated with pupillary dilation in a patient with exfoliation glaucoma taking anticoagulation therapy.

Methods: A 78-year-old woman with bilateral exfoliation glaucoma who was receiving warfarin, 2 mg daily, for systemic anticoagulation developed acute visual loss in the right eye several hours after pupillary dilation.

Result: Examination disclosed bilateral advanced exfoliation glaucoma, localized vascularized iridolenticular adhesions in the right eye, and a 4-mm layered hyphema in the right eye.

Conclusion: Patients with exfoliation glaucoma and vascularized posterior synechiae who are receiving anticoagulation therapy are at increased risk for visually significant spontaneous hyphema after pupillary dilation.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anticoagulants / therapeutic use*
  • Atrial Fibrillation / complications
  • Atrial Fibrillation / drug therapy
  • Carbachol / therapeutic use
  • Cerebrovascular Disorders / complications
  • Cerebrovascular Disorders / drug therapy
  • Drug Therapy, Combination
  • Exfoliation Syndrome / complications*
  • Female
  • Glaucoma / complications*
  • Glaucoma / drug therapy
  • Humans
  • Hyphema / etiology*
  • Latanoprost
  • Propranolol / therapeutic use
  • Prostaglandins F, Synthetic / therapeutic use
  • Pupil*
  • Warfarin / therapeutic use*

Substances

  • Anticoagulants
  • Prostaglandins F, Synthetic
  • Warfarin
  • Latanoprost
  • Carbachol
  • Propranolol