Abstract
We retrospectively examined the electrocardiograms in all of our patients with nonischemic dilated cardiomyopathy and normal sinus rhythm before and after at least 3 months of metoprolol (n = 12), bucindolol (n = 8), carvedilol (n = 6), or no beta blocker (n = 9). Both beta1-selective and nonselective beta-adrenergic blockade reduced QTc dispersion equally in patients with dilated cardiomyopathy.
MeSH terms
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Adrenergic beta-Antagonists / pharmacology*
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Adult
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Aged
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Carbazoles / pharmacology
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Cardiomyopathy, Dilated / drug therapy*
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Cardiomyopathy, Dilated / etiology
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Cardiomyopathy, Dilated / mortality
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Cardiomyopathy, Dilated / physiopathology
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Carvedilol
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Death, Sudden, Cardiac / prevention & control
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Electrocardiography / drug effects
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Female
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Heart Conduction System / drug effects*
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Humans
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Male
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Metoprolol / pharmacology
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Middle Aged
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Propanolamines / pharmacology
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Retrospective Studies
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Stroke Volume / drug effects
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Treatment Outcome
Substances
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Adrenergic beta-Antagonists
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Carbazoles
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Propanolamines
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Carvedilol
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bucindolol
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Metoprolol