Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1999 Aug;262(1):163-72.
doi: 10.1007/s004380051071.

Analysis of the cps1 Gene Provides Evidence for a Septation Checkpoint in Schizosaccharomyces Pombe

Affiliations

Analysis of the cps1 Gene Provides Evidence for a Septation Checkpoint in Schizosaccharomyces Pombe

X Le Goff et al. Mol Gen Genet. .

Abstract

The fission yeast gene cps1, which encodes the catalytic subunit of beta-glucan synthase, was isolated in a screen for mutants that show an increase in ploidy at the restrictive temperature. cps1 mutants display defects in both polarity and septation at the permissive temperature, and become swollen and multinucleate at the restrictive temperature. Analysis of the interaction of cps1 with other mutations suggests the existence of a septation checkpoint, which requires the activity of the protein kinase weel for function.

Similar articles

See all similar articles

Cited by 46 articles

See all "Cited by" articles

Publication types

MeSH terms

LinkOut - more resources

Feedback