Fibrosing alveolitis predating microscopic polyangiitis

Scand J Rheumatol. 1999;28(4):254-6. doi: 10.1080/03009749950155643.


A 65 year old male was diagnosed with "cryptogenic fibrosing alveolitis (CFA)" and treated successfully with Prednisone. In the year following Prednisone-tapering he presented with livedo reticularis, segmental pauci-immune glomerulonephritis and necrotizing vasculitis of the peripheral nerves, increased pulmonary fibrosis, and the presence of p-ANCA antibodies. Aggressive immunosuppressive treatment of this microscopic polyangiitis (MPA) was successful and also resulted in stabilization of the pulmonary fibrosis. This case illustrates that MPA may present itself monosymptomatic as CFA.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Glomerulonephritis / diagnosis
  • Glomerulonephritis / physiopathology
  • Humans
  • Male
  • Necrosis
  • Peripheral Nervous System Diseases / diagnosis
  • Prednisone / therapeutic use
  • Pulmonary Fibrosis / drug therapy
  • Pulmonary Fibrosis / physiopathology*
  • Vasculitis / diagnosis*
  • Vasculitis / pathology
  • Vasculitis / physiopathology


  • Prednisone