Assembly and regulation of telomerase

Curr Opin Chem Biol. 1999 Oct;3(5):573-7. doi: 10.1016/s1367-5931(99)00011-3.

Abstract

Recent studies on the telomerase reverse transcriptase have benefited from the identification of the catalytic core subunits. Cellular factors that participate in the assembly of the core enzyme have been identified and regulatory mechanisms that control telomerase activity are beginning to be elucidated.

Publication types

  • Review

MeSH terms

  • Animals
  • Binding Sites
  • Humans
  • Sequence Analysis, DNA
  • Telomerase / metabolism*

Substances

  • Telomerase